Comparative retrospective study of biochemical and haematological biomarkers and their alterations in First and Second COVID-19 wave in a tertiary care facility in Ghaziabad

Juhi Aggarwal; Sojit Tomo; Jyoti Batra; Pradhumn Katara

doi:10.53730/ijhs.v6nS3.7737

Authors

Juhi Aggarwal Professor & Head, Department of Biochemistry, Santosh Medical College and Hospital, Ghaziabad, Uttar Pradesh -201009
Sojit Tomo Assistant Professor, Department of Biochemistry, Santosh Medical College and Hospital, Ghaziabad, Uttar Pradesh -201009
Jyoti Batra Professor, Department of Biochemistry, Santosh Medical College and Hospital, Ghaziabad, Uttar Pradesh -201009
Pradhumn Katara Assistant Professor Biostatistics, Department of Community Medicine Santosh Deemed to be University, Ghaziabad, Uttar Pradesh -201009

Keywords:

COVID-19, first wave, second wave, biochemical biomarkers, hematological biomarkers

Abstract

Background: The second wave of COVID-19 in India started in the middle of March 2021. In comparison to the first wave, the second wave of COVID-19 was characterized by a massive increase in the number of cases, reduced supplies of essential treatments, and increased deaths, particularly in the young population. In addition, the second wave was also characterized by the reporting of numerous cases of mucormycosis. Surprisingly, it was the younger population who were more affected in the second wave of the disease. The distinct difference in the first and second waves of COVID-19 in India makes it imperative to study the biochemical and pathological differences between the two. Methods: We aimed to assess the biochemical and pathological biomarkers and their alterations in 1^st and 2^nd waves of COVID-19 in a tertiary care L3 facility in Ghaziabad. Reports of haematological and biochemical parameters of the admitted patients were compiled retrospectively for statistical analysis based on the severity status of the patient and were compared between the first wave and second wave of COVID-19.

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