Biochemical cardiac markers: An index in the assessment/diagnosis of cardiovascular changes in type-2 diabetic patients

Niharika Singh; Juhi Aggarwal; Jyoti Batra; Nitin Srivastava

doi:10.53730/ijhs.v6nS2.8421

Authors

Niharika Singh 1 PhD Scholar, Department of Biochemistry, Santosh Medical College and Hospital, Ghaziabad, Uttar Pradesh -201009
Juhi Aggarwal Professor and Head, Department of Biochemistry, Santosh Medical College and Hospital, Ghaziabad, Uttar Pradesh -201009
Jyoti Batra Dean Research and Professor, Department of Biochemistry, Santosh Medical College and Hospital, Ghaziabad, Uttar Pradesh -201009
Nitin Srivastava Assistant Professor, Department of Medicine, MIMS, Barabanki, Uttar Pradesh-225001

Keywords:

creatine kinase, lactate dehydrogenase, glycated hemoglobin

Abstract

Aim: The aim of this study is to estimate the changes in cardiac markers in type 2 diabetic patients with and without cardiovascular changes. Methods: In this cross -sectional study, 240 patients with diabetes mellitus type 2 were recruited. The biochemical marker of each patient is compared . Blood samples were gathered and processed for the estimation of CK-MB, LDH, trop-t ,uric acid, microalbuminuria and HbA1c. Results: Diabetic individuals had high levels CK-MB, LDH, trop-t and uric acid as compared with and without (CVS)cardiovascular changes in diabetic patients.. Study suggested that cardiac marker levels were significantly increased in hypertensive patients who’s suffering from diabetes mellitus. Conclusion: There is a need for periodic assessment of the cardiac function and biochemical markers in diabetic patients so that patients can take early preventative measures. Early assessment of the cardiac function and biochemical markers provides early warning signals for patients to take additional precautions.

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