Formulation and evaluation of serratiopeptidase and salbutamol tablet for dysphagia

https://doi.org/10.53730/ijhs.v6nS3.8241

Authors

  • Onkar Kulkarni Dept of Pharmaceutical Quality Assurance, Pune District Education Association's Shankarrao Ursal College of Pharmaceutical Sciences & Research Centre, Kharadi
  • Amit Kasabe Dept of Pharmaceutical Quality Assurance, Pune District Education Association's Shankarrao Ursal College of Pharmaceutical Sciences & Research Centre, Kharadi
  • Vijaya Barge Dept of Pharmaceutical Quality Assurance, Pune District Education Association's Shankarrao Ursal College of Pharmaceutical Sciences & Research Centre, Kharadi
  • Vikram Kerle Dept of Pharmaceutical Quality Assurance, Pune District Education Association's Shankarrao Ursal College of Pharmaceutical Sciences & Research Centre, Kharadi
  • Abhijeet Pate Dept of Pharmaceutical Quality Assurance, Pune District Education Association's Shankarrao Ursal College of Pharmaceutical Sciences & Research Centre, Kharadi

Keywords:

fast dissolving tablets, mouth dissolving tablets, orally disintegrating tablets

Abstract

Oral Dispersible Tablet of Serratiopeptidase and salbutamol were prepared, evaluated and different types of concentration and dissolution of tablets were studied. In FTIR, drug and excipients with their mixture showed that there is no interaction between the drug molecule and excipients used. The Percentage of drug content of tablets in the formulations was found to be 95 % to 105% which complies with the limits of pharmacopoeia. By the process of direct compression method was used to prepare oral Dispersible tablet containing 300 mg of Serratiopeptidase and salbutamol. formulation was conducted using different concentrations of croscarmellose, micro crystalline cellulose, as a super disintegrants. And their interaction with Serratiopeptidase and salbutamol also evaluated using FTIR.

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Published

01-06-2022

How to Cite

Kulkarni, O., Kasabe, A., Barge, V., Kerle, V., & Pate, A. (2022). Formulation and evaluation of serratiopeptidase and salbutamol tablet for dysphagia. International Journal of Health Sciences, 6(S3), 9154–9169. https://doi.org/10.53730/ijhs.v6nS3.8241

Issue

Section

Peer Review Articles