Histopathological findings of umbilical cord in intrauterine growth restriction

Sudhakara Babu Chelli; S M Surekha; P Upendhar Reddy; Govindarajan Sumathy

doi:10.53730/ijhs.v6nS2.8465

Authors

Sudhakara Babu Chelli Ph.D. Scholar, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu
Surekha S M Associate Professor, Department of Obstetrics and Gynecology, KIMS, Koppal, Karnataka
Upendhar Reddy P Assistant Professor, Department of Anatomy, SVS Medical College, Mahbubnagar, Telangana
Govindarajan Sumathy Prof. & HOD, Department of Anatomy, Sree Balaji dental college & hospital, Chennai, Tamil Nadu

Keywords:

intrauterine growth restriction, histopathology, Wharton’s jelly oedema, venous dilatation

Abstract

Background: Intrauterine growth restriction is one of the causes of perinatal mortality and morbidity. Intrauterine growth of fetus depends on maternal, fetal and genetic factors. Aim of the study was to find the histopathology of umbilical cord in IUGR and normal pregnancies. Materials & methods: This prospective case control study included 100 umbilical cord samples which were equally distributed as cases and control. Routine histological procedures were followed for staining of tissue. Histopathology readings were photographed and noted. Results: In our study we found 24 % Wharton’s jelly oedema and 28 % venous dilatations in IUGR. We didn’t observe any thrombus, fibrinoid necrosis, perivascular or intraparietal hemorrhage, arterial or venous thrombus in our study both in cases and control. Conclusion: Umbilical cord and placental histopathology provides insight to predict reoccurrence of IUGR and for timely management.

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