Biofluids in orofacial pain
Review
Keywords:
biofluid, biomarkers, neural pain, serum, salivaAbstract
Orofacial pain is a dental specialty that focuses on diagnosing and treating long-term, complicated facial discomfort caused by oromotor disorders. This pain is similar to pain elsewhere in the body and is generally caused by tissue damages. The pathogenesis of orofacialpain might be caused by orofacial structures illness, musculoskeletal system disorders, peripheral or central nervous system disorders, systemic diseases, psychological problems, or the result of inadequate sleep. One method to diagnose is evaluating the molecular and microbial cues of biological fluids, which may indicate the occurrence or progression of the disease. This article provides an overview of these biofluids and biomarkers and their role in progression of orofacial diseases.
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