The role of nanotechnology in restorative dentistry
A review of current applications
Keywords:
Nanotechnology, restorative dentistry, dental composites, nanomaterials, adhesives, antibacterial agents, dental cements, tooth whiteningAbstract
Background: Restorative dentistry has evolved significantly from the use of traditional materials such as amalgam to more advanced options like dental composite resins. Nanotechnology, which involves manipulating materials at the atomic or molecular scale, has introduced a new dimension to dental materials, offering improvements in mechanical properties, aesthetics, and functionality. Aim: This review aims to explore the current applications of nanotechnology in restorative dentistry, focusing on how nanomaterials enhance dental treatments and restorations. Methods: A comprehensive review of recent studies and advancements in nanomaterials applied to dental composite resins, adhesives, cements, and whitening agents was conducted. Key areas of investigation included the impact of nanomaterials on mechanical strength, wear resistance, antibacterial properties, and aesthetic outcomes. Results: Nanomaterials such as nanoparticles of silica, zirconia, titanium dioxide, silver, and zinc oxide have been integrated into dental materials to improve their performance. Nanocomposites demonstrate enhanced mechanical strength and durability, while nano-enhanced adhesives offer better bonding and self-healing capabilities. Antibacterial properties have been significantly improved with silver and zinc oxide nanoparticles, which help in preventing secondary caries and oral infections. Nanomaterials have also advanced dental cements and whitening agents, offering better fluoride release, controlled whitening effects, and improved imaging techniques.
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References
Roco, M. C. (2003). Nanotechnology: Convergence with modern biology and medicine. Current Opinion in Biotechnology, 14(3), 337–346.
Deyhle, H., Oliver, B., Buser, S., et al. (2009). Bio-inspired dental fillings. In Proceedings of the Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series (Vol. 7401).
Goldberg, M., Kulkarni, A. B., Young, M., & Boskey, A. (2011). Dentin: Structure, composition and mineralization. Frontiers in Bioscience (Elite Edition), 3, 711–735.
Kumar, P. S., Kumar, S., Savadi, R. C., & John, J. (2011). Nanodentistry: A paradigm shift—from fiction to reality. Journal of the Indian Prosthodontic Society, 11(1), 1–6.
Gaiser, S., Deyhle, H., Bunk, O., White, S. N., & Müller, B. (2012). Understanding nano-anatomy of healthy and carious human teeth: A prerequisite for nanodentistry. Biointerphases, 7(4).
Besinis, A., De Peralta, T., Tredwin, C. J., & Handy, R. D. (2015). Review of nanomaterials in dentistry: Interactions with the oral microenvironment, clinical applications, hazards, and benefits. ACS Nano,9(3), 2255–2289.
Ateyah, N. (2013). Mechanical behavior of water-aged nano-filled hybrid composite restoratives. King Saud University Journal of Dental Sciences, 4(1), 21–25.
Mitra, S. B., Oxman, J. D., Falsafi, A., & Ton, T. T. (2011). Fluoride release and recharge behavior of a nano-filled resin-modified glass ionomer compared with that of other fluoride releasing materials. American Journal of Dentistry, 24(6), 372–378. Retrieved from https://pubmed.ncbi.nlm.nih.gov/22263336
Khurshid, Z., Zafar, M. S., Qasim, S., Shahab, S., Naseem, M., & AbuReqaiba, A. (2015). Advances in nanotechnology for restorative dentistry. Materials (Basel), 8(9), 717–731.
Jain, A. K., Deepti, D., Tavane, P. N., Singh, A., Gupta, P. K., Gupta, A., & Sonkusre, S. (2015). Evaluation of microleakage of recent nano-hybrid composites in class V restorations: An in vitro study. International Journal of Advanced Health Sciences, 2(2), 8–12. Retrieved from https://www.semanticscholar.org/paper/Evaluation-of-Microleakage-of-Recent-Nano-hybrid-in-Jain-Deepti/3c8a5bb9cbe4d35d941d5e96bd19da4a6b8514c9
Foong, L. K., Foroughi, M. M., Mirhosseini, A. F., et al. (2020). Applications of nano-materials in diverse dentistry regimes. RSC Advances, 10(24), 15430–15460.
Xiao, S., Liang, K., Weir, M. D., et al. (2017). Combining bioactive multifunctional dental composite with PAMAM for root dentin remineralization. Materials (Basel), 10(1), 89.
Ghahremani, L., Shirkavand, S., Akbari, F., & Sabzikari, N. (2017). Tensile strength and impact strength of color modified acrylic resin reinforced with titanium dioxide nanoparticles. Journal of Clinical & Experimental Dentistry, 9(6), e0–e5.
Meena, A., Mali, H. S., Patnaik, A., & Kumar, S. R. (2016). Effect of adding nanoalumina and marble dust powder on the physical, mechanical, and thermo-mechanical characterization of dental composite. Polymer Composites, 39(1), 0–31.
Wang, R., Habib, E., & Zhu, X. X. (2018). Evaluation of the filler packing structures in dental resin composites: From theory to practice. Dental Materials, 34(7), 1014–1023.
Al-Eisa, A., Al-Mosawi, M., Gupta, R., D’Souza, T. M., & Sharma, P. N. (2000). Attitudes of general practitioners and pediatricians to management of acute pyelonephritis in children. Medical Principles and Practice, 9(2), 119–124.
Ai, M., Du, Z., Zhu, S., Geng, H., Zhang, X., Cai, Q., & Yang, X. (2017). Composite resin reinforced with silver nanoparticles-laden hydroxyapatite nanowires for dental application. Dental Materials, 33(1), 12–22.
Paiva, L., Fidalgo, T. K., da Costa, L. P., et al. (2018). Antibacterial properties and compressive strength of new one-step preparation silver nanoparticles in glass ionomer cements (NanoAg-GIC). Journal of Dentistry, 69, 102–109.
Hübner, N. O., Siebert, J., & Kramer, A. (2010). Octenidine dihydrochloride, a modern antiseptic for skin, mucous membranes and wounds. Skin Pharmacology and Physiology, 23(5), 244–258
Al-Doori, Z., Goroncy-Bermes, P., Gemmell, C. G., & Morrison, D. (2007). Low-level exposure of MRSA to octenidine dihydrochloride does not select for resistance. Journal of Antimicrobial Chemotherapy, 59(6), 1280–1281.
Stewart, C. A., Hong, J. H., Hatton, B. D., & Finer, Y. (2018). Responsive antimicrobial dental adhesive based on drug-silica co-assembled particles. Acta Biomaterialia, 76, 283–294.
Yue, S., Wu, J., Zhang, Q., et al. (2018). Novel dental adhesive resin with crack self-healing, antimicrobial and remineralization properties. Journal of Dentistry, 75, 48–57.
Cao, W., Zhang, Y., Wang, X., et al. (2017). Development of a novel resin-based dental material with dual biocidal modes and sustained release of Ag(+) ions based on photocurable core-shell AgBr/cationic polymer nanocomposites. Journal of Materials Science: Materials in Medicine, 28(8), 103.
Kasraei, S., Sami, L., Hendi, S., Alikhani, M. Y., Rezaei-Soufi, L., & Khamverdi, Z. (2014). Antibacterial properties of composite resins incorporating silver and zinc oxide nanoparticles on Streptococcus mutans and Lactobacillus. Restorative Dentistry & Endodontics, 39(2), 109–114.
Andrade, V., Martínez, A., Rojas, N., Bello-Toledo, H., Flores, P., Sánchez-Sanhueza, G., & Catalán, A. (2018). Antibacterial activity against Streptococcus mutans and diametrical tensile strength of an interim cement modified with zinc oxide nanoparticles and terpenes: An in vitro study. Journal of Prosthetic Dentistry, 119(6), 862–867.
Dutra-Correa, M., Leite, A. A., de Cara, S. P., et al. (2018). Antibacterial effects and cytotoxicity of an adhesive containing low concentration of silver nanoparticles. Journal of Dentistry, 77, 66–71.
Cao, W., Zhang, Y., Wang, X., et al. (2018). Novel resin-based dental material with anti-biofilm activity and improved mechanical property by incorporating hydrophilic cationic copolymer functionalized nanodiamond. Journal of Materials Science: Materials in Medicine, 29(1), 162.
Renné, W. G., Lindner, A., Mennito, A. S., et al. (2017). Antibacterial properties of copper iodide-doped glass ionomer-based materials and effect of copper iodide nanoparticles on collagen degradation. Clinical Oral Investigations, 21(1), 369–379.
Alatawi, R. A., Elsayed, N. H., & Mohamed, W. S. (2019). Influence of hydroxyapatite nanoparticles on the properties of glass ionomer cement. Journal of Materials Research and Technology, 8(1), 344–349.
Xie, X., Wang, L., Xing, D., et al. (2017). Novel dental adhesive with triple benefits of calcium phosphate recharge, protein-repellent and antibacterial functions. Dental Materials, 33(5), 553–563.
Mandhalkar, R., Paul, P., & Reche, A. (2023). Application of nanomaterials in restorative dentistry. Cureus, 15(1).
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